Overview
MIC + B12 injections are compounded prescription medications that combine methionine, inositol, and choline (the “MIC” lipotropic agents) with vitamin B12 (methylcobalamin or hydroxocobalamin). These compounds play supportive roles in liver function, metabolism, and energy processes within the body.
This injection is formulated for intramuscular (IM) or subcutaneous (SubQ) administration under the supervision of a licensed clinician.
Important Safety Information
- Use only as prescribed by your licensed clinician.
- Do not share this medication with others.
- Report any side effects to your healthcare provider or pharmacist.
- Seek medical attention immediately if you experience:
- Chest pain or palpitations
- Shortness of breath or severe dizziness
- Rash, itching, swelling, or hives
- Numbness, tingling, or weakness in the limbs
- Persistent fatigue or unexplained mood changes
- Mild soreness or redness at the injection site may occur and is usually temporary.
- Compounded sterile injectables carry a small risk of contamination if not prepared or handled properly. Always confirm your medication is dispensed from a licensed and compliant pharmacy.
Consult Your Healthcare Provider
Always inform your primary care provider and all other healthcare professionals about every prescription, over-the-counter medication, and supplement you take.
This helps prevent drug interactions and ensures coordinated, safe care.
Warnings and Precautions
- Do not use if you have a known allergy to cobalamin (vitamin B12), methionine, inositol, or choline.
- Use caution if you have liver disease, kidney impairment, or gout, as methionine metabolism can influence homocysteine levels.
- Safety during pregnancy or breastfeeding has not been established; use only under medical supervision.
- Injections should be administered by or under the direction of a licensed clinician using sterile technique.
Drug Interactions
- Chloramphenicol, certain antibiotics, or methotrexate may interfere with the effectiveness of vitamin B12.
- Levodopa (used for Parkinson’s disease) may interact with B vitamins, potentially altering its effects.
- Alcohol and chronic use of certain acid-reducing medications can affect vitamin B12 absorption and metabolism.
- Provide your clinician with a complete list of all medications, supplements, and vitamins you take.
Use and Administration
- Administer by intramuscular (IM) or subcutaneous (SubQ) injection only as directed by your prescribing clinician.
- Do not change your dose or frequency without medical guidance.
- Store according to label instructions — typically refrigerated and protected from light.
- Do not freeze.
- Keep out of reach of children.
FDA and Compounding Disclaimer
Some medications offered through our platform may include compounded products that have not been approved by the U.S. Food and Drug Administration (FDA).
The FDA does not verify the safety or effectiveness of compounded drugs, including MIC + B12 Injection.
Our specialists may prescribe this medication off-label from its originally approved use based on clinical judgment and patient need.
Last Updated: October 7, 2025